Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | AKT1 | P31749 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.39 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833014 | 0.91 | LMNA (0.58) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL13619237 | 0.91 | LMNA (0.58) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL14447829 | 0.84 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL60426 | 0.84 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL14447974 | 0.84 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL5707895 | 0.84 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL905581 | 0.84 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL60848 | 0.84 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL14447816 | 0.84 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A | |
| SCHEMBL2693659 | 0.84 | LMNA (0.70) | LMNAAKT1ESR1ADORA3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637309-B1 | METAL COATINGS | BIOCOMPATIBLES LTD (GB) | 1999-03-31 | — | — | EP | disclosed |
| US-5556710-A | METAL COATINGS TO RENDER SURFACES BIOCOMPATIBLE | BIOCOMPATIBLES LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |