SCHEMBL852224

SCHEMBL852224

c1ccc(C2=C(c3ccccc3)C(c3ccccc3)=C2c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.67
MAPK1 P28482 2/20 0.47
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
PDE4B Q07343 1/20 0.46
HSD17B10 Q99714 3/20 0.44
BCL2L1 Q07817 2/20 0.44
CYP1A2 P05177 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
CYP3A4 P08684 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NOTUM Q6P988 1/20 0.44
MMP3 P08254 1/20 0.44
KMT2A Q03164 2/20 0.43
BACE1 P56817 1/20 0.42
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL532969 1.00 ALDH1A1 (0.67) ALDH1A1MAPK1RAB9ANPC1PDE4B
SCHEMBL532970 1.00 ALDH1A1 (0.67) ALDH1A1MAPK1RAB9ANPC1PDE4B
SCHEMBL8980173 0.96 ALDH1A1 (0.61) ALDH1A1MAPK1RAB9ANPC1PDE4B
SCHEMBL31290735 0.96 ALDH1A1 (0.61) ALDH1A1MAPK1RAB9ANPC1PDE4B
SCHEMBL8440556 0.96 ALDH1A1 (0.61) ALDH1A1MAPK1RAB9ANPC1PDE4B
SCHEMBL6414357 0.86 ALDH1A1 (0.50) ALDH1A1MAPK1RAB9ANPC1PDE4B
SCHEMBL4936702 0.86 ALDH1A1 (0.50) ALDH1A1MAPK1RAB9ANPC1PDE4B
SCHEMBL4437887 0.86 ALDH1A1 (0.50) ALDH1A1MAPK1RAB9ANPC1PDE4B
SCHEMBL17711598 0.83 BCL2L1 (0.48) ALDH1A1RAB9ANPC1PDE4BHSD17B10
SCHEMBL516326 0.83 PDE4B (0.54) ALDH1A1MAPK1RAB9ANPC1PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114196210-B Application of organic silicon material in 3D printing 中化化工科学技术研究总院有限公司 2023-08-04 CN claimed
EP-0597613-B1 Infrared radiation curable organopolysiloxane compositions GEN ELECTRIC (US) 2001-01-31 EP claimed
US-5384357-A Infrared radiation curable organopolysiloxane compositions GENERAL ELECTRIC COMPANY (US) 1995-01-24 US claimed
EP-0022271-B1 DOPED POLYACETYLENES AND THEIR PRODUCTION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1985-01-09 EP claimed
US-4349664-A Doped acetylene polymer and process for production thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-09-14 US claimed
EP-0022271-A1 Doped polyacetylenes and their production JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-01-14 EP claimed
CN-116178647-B Cobalt cyclopentadiene-based covalent organic framework material, preparation method and application thereof 中国石油大学(华东) 2025-02-14 CN disclosed
US-20240336502-A1 ELECTROCHEMICAL DEVICES OR SYSTEMS COMPRISING REDOX-FUNCTIONALIZED ELECTRODES AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-10-10 US disclosed
US-11945737-B2 Electrochemical devices or systems comprising redox-functionalized electrodes and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-04-02 US disclosed
US-11917906-B2 Compounds that can be used in an organic electronic device MERCK PATENT GMBH (DE) 2024-02-27 US disclosed
CN-114196210-B Application of organic silicon material in 3D printing 中化化工科学技术研究总院有限公司 2023-08-04 CN disclosed
CN-116178647-A Cobalt cyclopentadiene-based covalent organic framework material, preparation method and application thereof 中国石油大学(华东) 2023-05-30 CN disclosed
CN-114196210-A Application of organic silicon material in 3D printing 中化化工科学技术研究总院有限公司 2022-03-18 CN disclosed
US-5332538-A Method for making a spacer element for a multi-pane sealed window GENERAL ELECTRIC COMPANY (US) 1994-07-26 US disclosed
EP-0597613-A1 Infrared radiation curable organopolysiloxane compositions GENERAL ELECTRIC COMPANY (US) 1994-05-18 EP disclosed
EP-0596677-A1 Method for making a spacer element for a multi-pane sealed window GENERAL ELECTRIC COMPANY (US) 1994-05-11 EP disclosed
US-4496700-A Polymerization of haloalkynes by a nickel catalyst UNION CARBIDE CORPORATION (US) 1985-01-29 US disclosed
EP-0022271-B1 DOPED POLYACETYLENES AND THEIR PRODUCTION JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1985-01-09 EP disclosed
US-4349664-A Doped acetylene polymer and process for production thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-09-14 US disclosed
EP-0022271-A1 Doped polyacetylenes and their production JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-01-14 EP disclosed