SCHEMBL8522279

SCHEMBL8522279

CC=CC(=O)Oc1ccccc1CCCCCCC

nearest known ligand 0.73

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRA P10827 2/20 0.73
THRB P10828 2/20 0.73
PPARA Q07869 3/20 0.50
PPARG P37231 2/20 0.50
LIPG Q9Y5X9 1/20 0.45
ALOX5 P09917 1/20 0.44
PTGS2 P35354 1/20 0.44
ZDHHC2 Q9UIJ5 1/20 0.44
BID P55957 3/20 0.43
MCL1 Q07820 3/20 0.43
BCL2L1 Q07817 2/20 0.43
BAK1 Q16611 2/20 0.43
KAT8 Q9H7Z6 2/20 0.43
EP300 Q09472 1/20 0.43
KAT2A Q92830 1/20 0.43
KAT2B Q92831 1/20 0.43
KAT5 Q92993 1/20 0.43
SAE1 Q9UBE0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5297313 1.00 THRA (0.73) THRATHRBPPARAPPARGLIPG
SCHEMBL8522277 1.00 THRA (0.73) THRATHRBPPARAPPARGLIPG
SCHEMBL5297327 1.00 THRA (0.73) THRATHRBPPARAPPARGLIPG
SCHEMBL2491191 0.99 THRA (0.71) THRATHRBPPARAPPARGLIPG
SCHEMBL11037912 0.93 THRA (0.79) THRATHRBPPARAPPARGLIPG
SCHEMBL11037918 0.93 THRA (0.79) THRATHRBPPARAPPARGLIPG
SCHEMBL9773365 0.93 THRA (0.79) THRATHRBPPARAPPARGLIPG
SCHEMBL9773379 0.93 THRA (0.79) THRATHRBPPARAPPARGLIPG
SCHEMBL6755908 0.89 THRA (0.77) THRATHRBPPARAPPARGLIPG
SCHEMBL27634436 0.88 THRA (0.56) THRATHRBALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0942651-A1 INSECTICIDAL AND MITICIDAL COMPOSITIONS AMERICAN CYANAMID COMPANY (US) 1999-09-22 EP claimed
WO-1998023154-A1 INSECTICIDAL AND MITICIDAL COMPOSITIONS AMERICAN CYANAMID COMPANY (US) 1998-06-04 WO claimed