Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 15/20 | 0.73 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL7553163 | 0.93 | TLR7 (0.65) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL29508382 | 0.85 | TLR7 (1.00) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL189202 | 0.85 | TLR7 (1.00) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL10732746 | 0.82 | TLR7 (0.51) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL6719054 | 0.81 | TLR7 (0.50) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL9602030 | 0.80 | TLR7 (0.47) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL9601993 | 0.80 | CYP11B1 (0.50) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL9385147 | 0.80 | TLR7 (0.47) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL1774913 | 0.79 | TLR7 (0.72) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL29378640 | 0.79 | TLR7 (0.72) | TLR7NUDT1LMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939526-B2 | Sulfone substituted imidazo ring ethers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2011-05-10 | — | — | US | disclosed |
| US-20070155767-A1 | Sulfone substituted imidazo ring ethers | 3M INNOVATIVE PROPERTIES COMPANY | 2007-07-05 | — | — | US | disclosed |
| CN-1914203-A | Sulfone substituted imidazo ring ethers | 3M INNOVATIVE PROPERTIES CO (US) | 2007-02-14 | — | — | CN | disclosed |
| EP-1694674-A2 | SULFONE SUBSTITUTED IMIDAZO RING ETHERS | 3M Innovative Properties Company (US) | 2006-08-30 | — | — | EP | disclosed |
| US-7026482-B2 | Process for preparing imidazoquinolinamines | MEDICIS PHARMACEUTICAL CORPORATION | 2006-04-11 | — | — | US | disclosed |
| WO-2005076783-A2 | SULFONE SUBSTITUTED IMIDAZO RING ETHERS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-08-25 | — | — | WO | disclosed |
| US-6897314-B2 | Process for preparing imidazoquinolinamines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-05-24 | — | — | US | disclosed |
| US-20050096470-A1 | Process for preparing imidazoquinolinamines | 3M INNOVATIVE PROPERTIES COMPANY | 2005-05-05 | — | — | US | disclosed |
| EP-0912565-B1 | PROCESS FOR PREPARING IMIDAZOQUINOLINAMINES | MINNESOTA MINING & MFG (US) | 2004-04-14 | — | — | EP | disclosed |
| US-6624305-B2 | Reacting a 6H-imidazo(4,5-c) tetrazolo(1,5-a)quinoline with triphenylphosphine and hydrolyzing | 3M INNOVATIVE PROPERTIES COMPANY | 2003-09-23 | — | — | US | disclosed |
| US-5998619-A | Process for preparing imidazoquinolinamines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 1999-12-07 | — | — | US | disclosed |
| US-5741908-A | Process for reparing imidazoquinolinamines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5693811-A | Process for preparing tetrahdroimidazoquinolinamines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5602256-A | Process for 1H-imidazo[4,5-C]quinolines | RIKER LABORATORIES, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| US-5578727-A | Process for 1H-imidazo[4,5-c]quinolines | RIKER LABORATORIES, INC. (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0425306-B1 | Process for 1H-imidazo[4,5-c]-quinolines | RIKER LABORATORIES INC (US) | 1995-08-23 | — | — | EP | disclosed |
| EP-0425306-A2 | Process for 1H-imidazo[4,5-c]-quinolines | RIKER LABORATORIES, INC. (US) | 1991-05-02 | — | — | EP | disclosed |
| US-4988815-A | 3-Amino or 3-nitro quinoline compounds which are intermediates in preparing 1H-imidazo[4,5-c]quinolines | RIKER LABORATORIES, INC. (US) | 1991-01-29 | — | — | US | disclosed |
| US-4698348-A | 1H-imidazo[4,5-c]quinolines and their use as bronchodilating agents | RIKER LABORATORIES, INC. (US) | 1987-10-06 | — | — | US | disclosed |
| US-4689338-A | 1H-Imidazo[4,5-c]quinolin-4-amines and antiviral use | RIKER LABORATORIES, INC. (US) | 1987-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155767-A1 | Sulfone substituted imidazo ring ethers | IL2, IL4, IFNG | TLR7 82/4885NUDT1 2054/4885LMNA 4796/4885 |
| US-20050096470-A1 | Process for preparing imidazoquinolinamines | ITPA, INMT, PIP4K2C | TLR7 2042/4885NUDT1 15/4885LMNA 1093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.