SCHEMBL8522325

SCHEMBL8522325

CCCCCOC1C=CCC1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 6/20 0.41
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
PTAFR P25105 1/20 0.33
MEN1 O00255 1/20 0.31
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPT P10636 1/20 0.31
USP2 O75604 1/20 0.30
ALOX15 P16050 1/20 0.30
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11501663 0.94 SMN1; SMN2 (0.34) GBA1ALDH1A1TDP1USP2ALOX15
SCHEMBL6560470 0.89 GBA1 (0.39) GBA1ALDH1A1TDP1
SCHEMBL11324571 0.87 GBA1 (0.42) GBA1ALDH1A1TDP1PTAFRMEN1
SCHEMBL11328512 0.86
SCHEMBL10304159 0.83 SMN1; SMN2 (0.32) GBA1
SCHEMBL17472537 0.77
SCHEMBL7165503 0.75 GBA1 (0.47) GBA1ALDH1A1TDP1TP53CYP3A4
SCHEMBL16254144 0.75
SCHEMBL10169614 0.74 CYP1A2 (0.31)
SCHEMBL17616826 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0685450-B1 Process for the preparation of esters of carboxylic acids derived from allylic alcohol FIRMENICH & CIE (CH) 1999-07-14 EP disclosed
US-5554786-A Process for the preparation of carboxylic esters defined from allylic alcohols FIRMENICH S.A. (CH) 1996-09-10 US disclosed
EP-0685450-A1 Process for the preparation of esters of carboxylic acids derived from allylic alcohol FIRMENICH SA (CH) 1995-12-06 EP disclosed