Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932320 | 1.00 | TRPA1 (0.68) | TRPA1MAOAMAOBHPGDHTT | |
| SCHEMBL114824 | 0.82 | PTGS1 (0.48) | TRPA1 | |
| SCHEMBL358059 | 0.80 | TAAR1 (0.59) | TRPA1KMT2ATAAR1SLC6A2 | |
| SCHEMBL358607 | 0.80 | TAAR1 (0.59) | TRPA1KMT2ATAAR1SLC6A2 | |
| SCHEMBL8293621 | 0.80 | TRPA1 (0.44) | TRPA1HPGDIDO1TAAR1SLC6A2 | |
| SCHEMBL8056894 | 0.80 | TAAR1 (0.59) | TRPA1KMT2ATAAR1SLC6A2 | |
| SCHEMBL12197642 | 0.80 | TRPA1 (0.44) | TRPA1HPGDIDO1TAAR1SLC6A2 | |
| SCHEMBL10206049 | 0.80 | TRPA1 (0.44) | TRPA1HPGDIDO1TAAR1SLC6A2 | |
| SCHEMBL24244793 | 0.80 | TRPA1 (0.53) | TRPA1MAOAMAOBHPGDIDO1 | |
| SCHEMBL13165979 | 0.80 | TRPA1 (0.53) | TRPA1MAOAMAOBHPGDIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644775-B1 | Cocaine Receptor Binding Ligands | RES TRIANGLE INST (US) | 1999-08-04 | — | — | EP | disclosed |