SCHEMBL8522860

SCHEMBL8522860

C=C(C)C(=O)OC(CC)O[SiH](C)C

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1403514 0.86 ALDH1A1 (0.38) TSHRALDH1A1THRB
SCHEMBL601418 0.84 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL5068871 0.82 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL9162961 0.82 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL28528795 0.80 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL8968857 0.79 TSHR (0.41) TSHRALDH1A1THRB
Methacrylic Acid SCHEMBL6545289 0.79 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL554126 0.79 ALDH1A1 (0.44) TSHRALDH1A1THRB
SCHEMBL9741483 0.77 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL3624164 0.77 TSHR (0.39) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0769513-B1 Curable resin composition NIPPON PAINT CO LTD (JP) 1999-11-17 EP disclosed
US-5674569-A CURING UNDERCOATINGS, CLEAR TOP COATINGS CONCURRENTLY OR SEPARATLY, THE TOP COATINGS COMPRISING A BLEND OF A RESIN WITH PLURAL HYDROSILYL GROUP OR A POLYHYDROGENSILOXANE HOMO-OR COPOLYMER NIPPON PAINT CO., LTD. (JP) 1997-10-07 US disclosed
EP-0769513-A1 Curable resin composition NIPPON PAINT CO., LTD. (JP) 1997-04-23 EP disclosed
US-5599883-A COATING MIXTURES ALSO CONTAINING HYDROSILATION CATALYST NIPPON PAINT CO., LTD. (JP) 1997-02-04 US disclosed
EP-0702068-A1 Method of forming multilayer coatings on a substrate Nippon Paint Co., Ltd. (JP) 1996-03-20 EP disclosed
EP-0630943-A2 Curable resin composition Nippon Paint Co., Ltd. (JP) 1994-12-28 EP disclosed