Urethane

Urethane

SCHEMBL8522932

CCOC(N)=O.OCOCO

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.75
ALDH1A1 P00352 6/20 0.43
LMNA P02545 4/20 0.42
HSD17B10 Q99714 3/20 0.42
GAA P10253 4/20 0.40
MGAM O43451 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
SOAT1 P35610 1/20 0.40
CHRM2 P08172 2/20 0.38
CHRM4 P08173 2/20 0.38
CHRM5 P08912 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
TSHR P16473 2/20 0.38
CHRNB2 P17787 2/20 0.38
CHRNA4 P43681 2/20 0.38
HTR1A P08908 1/20 0.38
CYP2C19 P33261 1/20 0.38
CHRNA7 P36544 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL462241 0.87
Urethane SCHEMBL28110737 0.87
Urethane SCHEMBL27632514 0.87 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL8505249 0.87 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL8136 0.87
Urethane SCHEMBL8830978 0.87 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL8129017 0.87 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL367439 0.87 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL1450092 0.84 ALOX15 (0.83) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL11108306 0.84 ALOX15 (0.83) ALOX15ALDH1A1LMNAHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0245962-B2 Stabilized polyacetal compositions DU PONT (US) 1999-06-16 EP disclosed
EP-0242176-B1 Stabilized polyacetal compositions DU PONT (US) 1998-03-04 EP disclosed
CN-1007899-B STABILIZED POLYACETAL COMPOSITIONS DU PONT (US) 1990-05-09 CN disclosed
CN-1007898-B Stabilized polyoxymethylene compositions DU PONT (US) 1990-05-09 CN disclosed
US-4814397-A HEAT RESISTANT, BLENDS WITH HYDROXY CONTAINING POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-03-21 US disclosed
US-4766168-A ADDING HYDROXY CONTAINING POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-08-23 US disclosed
CN-87102759-A The polyformaldehyde composition of stabilization 1987-12-30 CN disclosed
EP-0245962-A2 Stabilized polyacetal compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-11-19 EP disclosed
CN-87102771-A The polyformaldehyde composition of stabilization 1987-10-28 CN disclosed
EP-0242176-A2 Stabilized polyacetal compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-10-21 EP disclosed