Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.53 |
| ▸ | MME | P08473 | 12/20 | 0.53 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030190 | 1.00 | ACE (0.53) | ACEMMEMMEL1PPARGPPARA | |
| SCHEMBL8017124 | 0.95 | MME (0.54) | ACEMMEMMEL1PPARGPPARA | |
| SCHEMBL8027621 | 0.91 | MME (0.65) | ACEMMEMMEL1PPARGPPARA | |
| SCHEMBL8523126 | 0.91 | MME (0.65) | ACEMMEMMEL1PPARGPPARA | |
| SCHEMBL8027626 | 0.91 | MME (0.65) | ACEMMEMMEL1PPARGPPARA | |
| SCHEMBL8027099 | 0.90 | MME (0.60) | ACEMMEMMEL1PPARGPPARD | |
| SCHEMBL8521923 | 0.90 | MME (0.60) | ACEMMEMMEL1PPARGPPARD | |
| SCHEMBL8448377 | 0.89 | MME (0.57) | ACEMMEPPARGPPARAPPARD | |
| SCHEMBL8030944 | 0.89 | MME (0.57) | ACEMMEPPARGPPARAPPARD | |
| SCHEMBL8030949 | 0.89 | MME (0.57) | ACEMMEPPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891912-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |