Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.54 |
| ▸ | ACE | P12821 | 12/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030190 | 0.95 | ACE (0.53) | MMEACEPPARGPPARAPPARD | |
| SCHEMBL8523133 | 0.95 | ACE (0.53) | MMEACEPPARGPPARAPPARD | |
| SCHEMBL8027609 | 0.91 | MME (0.66) | MMEACEPPARGPPARAPPARD | |
| SCHEMBL9007747 | 0.90 | MME (0.61) | MMEACEPPARGPPARDMMEL1 | |
| SCHEMBL8027145 | 0.89 | MME (0.67) | MMEACEPPARGPPARD | |
| SCHEMBL8017292 | 0.89 | MME (0.58) | MMEACEPPARGPPARAPPARD | |
| SCHEMBL8017295 | 0.89 | MME (0.58) | MMEACEPPARGPPARAPPARD | |
| SCHEMBL8017192 | 0.88 | MME (0.70) | MMEACEPPARGPPARD | |
| SCHEMBL8027626 | 0.85 | MME (0.65) | MMEACEPPARGPPARAPPARD | |
| SCHEMBL8523126 | 0.85 | MME (0.65) | MMEACEPPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |