Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852328 | 1.00 | L3MBTL1 (0.49) | L3MBTL1ALOX15HTTKDM4EALDH1A1 | |
| SCHEMBL1808376 | 0.82 | KDM4E (0.47) | L3MBTL1ALOX15KDM4EALDH1A1MAPT | |
| SCHEMBL1808375 | 0.82 | KDM4E (0.47) | L3MBTL1ALOX15KDM4EALDH1A1MAPT | |
| SCHEMBL9000394 | 0.79 | L3MBTL1 (0.51) | L3MBTL1ALOX15HTTKDM4EALDH1A1 | |
| SCHEMBL2561503 | 0.79 | L3MBTL1 (0.57) | L3MBTL1ALOX15HTTKDM4EALDH1A1 | |
| SCHEMBL21958052 | 0.78 | TDP1 (0.47) | L3MBTL1KDM4EALDH1A1NPC1MAPT | |
| SCHEMBL28636454 | 0.78 | TDP1 (0.47) | L3MBTL1KDM4EALDH1A1NPC1MAPT | |
| SCHEMBL21958100 | 0.78 | L3MBTL1 (0.39) | L3MBTL1ALOX15KDM4EALDH1A1NPC1 | |
| SCHEMBL535731 | 0.77 | L3MBTL1 (0.55) | L3MBTL1ALOX15HTTKDM4EALDH1A1 | |
| SCHEMBL21958073 | 0.76 | L3MBTL1 (0.48) | L3MBTL1ALOX15HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020264292-A1 | CXCR4 INHIBITORS AND USES THEREOF | X4 PHARMACEUTICALS, INC. (US) | 2020-12-30 | — | — | WO | disclosed |
| EP-2432783-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | Abbott Laboratories (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010135560-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2010-11-25 | — | — | WO | disclosed |