Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468822 | 0.77 | IDO1 (0.47) | IDO1METAP2METAP1NCEH1KDM4E | |
| SCHEMBL8523990 | 0.76 | EPHX1 (0.50) | IDO1NCEH1KDM4EALDH1A1MEN1 | |
| SCHEMBL8761385 | 0.75 | LMNA (0.40) | IDO1METAP2METAP1NCEH1KDM4E | |
| SCHEMBL8523292 | 0.73 | IDO1 (0.38) | IDO1METAP2METAP1PLK1NCEH1 | |
| SCHEMBL10719829 | 0.70 | IDO1 (0.58) | IDO1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8761891 | 0.68 | EPHX1 (0.48) | NCEH1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8761409 | 0.68 | EPHX1 (0.47) | NCEH1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8760458 | 0.67 | LMNA (0.38) | METAP2METAP1NCEH1KDM4EALDH1A1 | |
| SCHEMBL8761584 | 0.66 | KDM4E (0.40) | IDO1METAP2METAP1MTNR1AABCC9 | |
| SCHEMBL8761442 | 0.66 | KDM4E (0.40) | IDO1METAP2METAP1MTNR1AABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994270-A | CONTROLLING GAEUMANNOMYCES | MONSANTO COMPANY (US) | 1999-11-30 | — | — | US | disclosed |
| EP-0619297-B1 | Fungicides for the control of take-all desease of plants | MONSANTO CO (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0619297-A1 | Fungicides for the control of take-all desease of plants | MONSANTO COMPANY (US) | 1994-10-12 | — | — | EP | disclosed |