Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 20/20 | 0.78 |
| ▸ | ADRA1A | P35348 | 20/20 | 0.78 |
| ▸ | ADRA1B | P35368 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7952888 | 0.99 | ADRA1D (0.77) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7952891 | 0.99 | ADRA1D (0.77) | ADRA1DADRA1AADRA1B | |
| SCHEMBL8523556 | 0.82 | ADRA1D (0.65) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6218903 | 0.80 | ADRA1D (1.00) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6198376 | 0.78 | ADRA1D (1.00) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6198895 | 0.77 | ADRA1D (0.68) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7958027 | 0.76 | ADRA1D (0.58) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7944470 | 0.76 | ADRA1D (0.68) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6197192 | 0.75 | ADRA1D (0.69) | ADRA1DADRA1AADRA1B | |
| SCHEMBL6199928 | 0.75 | ADRA1D (0.69) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866708-A4 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 1999-05-06 | — | — | EP | disclosed |
| EP-0866708-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-09-30 | — | — | EP | disclosed |
| WO-1997017969-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-05-22 | — | — | WO | disclosed |