Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10281588 | 0.84 | PPARG (0.75) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL18388545 | 0.77 | PPARG (0.69) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL5935612 | 0.76 | KDM4E (0.74) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL29571968 | 0.76 | KDM4E (0.74) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| Balaglitazone SCHEMBL29362039 | 0.75 | PPARG (1.00) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| Balaglitazone SCHEMBL242011 | 0.75 | PPARG (1.00) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| Balaglitazone SCHEMBL20125575 | 0.75 | PPARG (1.00) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| Balaglitazone SCHEMBL20125574 | 0.75 | PPARG (1.00) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| SCHEMBL17471075 | 0.75 | PPARG (0.67) | KDM4EALOX15TSHRTDP1L3MBTL1 | |
| Balaglitazone SCHEMBL6359086 | 0.75 | PPARG (0.98) | KDM4EALOX15TSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958296-A1 | NOVEL HETEROCYCLIC COMPOUNDS PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED DISEASES | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-11-24 | — | — | EP | disclosed |
| WO-1997041097-A2 | NOVEL HETEROCYCLIC COMPOUNDS PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED DISEASES | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-11-06 | — | — | WO | disclosed |