Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15503338 | 1.00 | USP2 (0.41) | USP2TSHRTHRBHIF1ACYP3A4 | |
| SCHEMBL11257369 | 1.00 | USP2 (0.41) | USP2TSHRTHRBHIF1ACYP3A4 | |
| SCHEMBL11769969 | 0.98 | THRB (0.42) | USP2TSHRTHRBHIF1ACYP3A4 | |
| SCHEMBL12459957 | 0.98 | THRB (0.42) | USP2TSHRTHRBHIF1ACYP3A4 | |
| SCHEMBL1263525 | 0.91 | — | — | |
| SCHEMBL3441345 | 0.91 | — | — | |
| SCHEMBL13778515 | 0.91 | — | — | |
| SCHEMBL10085844 | 0.88 | TSHR (0.46) | USP2TSHRHIF1ACYP3A4SMN1; SMN2 | |
| SCHEMBL30132350 | 0.88 | TSHR (0.46) | USP2TSHRHIF1ACYP3A4SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL2197362 | 0.86 | THRB (0.46) | USP2TSHRTHRBHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002026-A | Catalytic oxygenation of hydrocarbons by metalloporphyrin and metallosalen complexes | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1999-12-14 | — | — | US | disclosed |
| WO-1998004538-A1 | CATALYTIC OXYGENATION OF HYDROCARBONS BY METALLOPORPHYRIN AND METALLOSALEN COMPLEXES | PRINCETON UNIVERSITY (US) | 1998-02-05 | — | — | WO | disclosed |