Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL11406906 | 0.96 | LMNA (0.77) | LMNAALDH1A1TSHRTHRBRECQL | |
| Dichloroacetic Acid SCHEMBL7777 | 0.91 | — | — | |
| Dichloroacetic Acid SCHEMBL5307050 | 0.91 | LMNA (1.00) | LMNAALDH1A1TSHRTHRBRECQL | |
| Dichloroacetic Acid SCHEMBL1331776 | 0.91 | — | — | |
| Dichloroacetic Acid SCHEMBL23923240 | 0.87 | — | — | |
| Dichloroacetic Acid SCHEMBL7263077 | 0.87 | — | — | |
| Dichloroacetic Acid SCHEMBL8610684 | 0.87 | — | — | |
| Dichloroacetic Acid SCHEMBL6913523 | 0.87 | — | — | |
| Dichloroacetic Acid SCHEMBL6914108 | 0.87 | — | — | |
| Dichloroacetic Acid SCHEMBL9682664 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923368-A1 | USE OF A HYBRID POLYMERIC MATERIAL FOR COATING KERATINOUS MATERIALS | L'OREAL (FR) | 1999-06-23 | — | — | EP | claimed |
| WO-1999002127-A1 | USE OF A HYBRID POLYMERIC MATERIAL FOR COATING KERATINOUS MATERIALS | L'OREAL (FR) | 1999-01-21 | — | — | WO | claimed |