Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CTH | P32929 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523818 | 1.00 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TAAR1NPC1RAB9A | |
| SCHEMBL12756955 | 1.00 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TAAR1NPC1RAB9A | |
| SCHEMBL28806335 | 0.81 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TAAR1NPC1RAB9A | |
| SCHEMBL9498067 | 0.80 | TAAR1 (0.61) | ALDH1A1SMN1; SMN2TAAR1NPC1RAB9A | |
| SCHEMBL9498059 | 0.80 | TAAR1 (0.61) | ALDH1A1SMN1; SMN2TAAR1NPC1RAB9A | |
| SCHEMBL9618380 | 0.78 | — | — | |
| SCHEMBL15043456 | 0.78 | — | — | |
| SCHEMBL9618381 | 0.78 | — | — | |
| SCHEMBL28073535 | 0.77 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2TAAR1NPC1RAB9A | |
| SCHEMBL9322281 | 0.76 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919796-A | ANTIISCHEMIC AGENTS | BIOREX KUTATO ES FEJLESZTO RT. (HU) | 1999-07-06 | — | — | US | disclosed |
| EP-0758315-B1 | NOVEL HYDROXIMIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | BIOREX KUTATO FEJLESZTOE KFT (HU) | 1998-08-26 | — | — | EP | disclosed |
| US-5532375-A | Process for preparing 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oximes | ROUSSEL-UCLAF (FR) | 1996-07-02 | — | — | US | disclosed |
| US-5391754-A | Oximination a tetrahydropyridin-3-aldehyde, alkylation with a halides, salt formation | ROUSSEL UCLAF (FR) | 1995-02-21 | — | — | US | disclosed |
| US-5219872-A | Treating Alzheimer*s disease, memory disorders | ROUSSEL UCLAF (FR) | 1993-06-15 | — | — | US | disclosed |
| US-5136038-A | Radiopharmaceuticals and chelating agents useful in their preparation | UNIVERSITY OF FLORIDA (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0239445-B1 | 1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXALDEHYDE OXIME DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE AS MEDICINES | ROUSSEL-UCLAF (FR) | 1992-05-13 | — | — | EP | disclosed |
| EP-0239445-A2 | 1,2,5,6-Tetrahydropyridine-3-carboxaldehyde oxime derivatives, process for their preparation, compositions containing them and their use as medicines | ROUSSEL-UCLAF (FR) | 1987-09-30 | — | — | EP | disclosed |
| EP-0191788-A1 | NOVEL RADIOPHARMACEUTICALS AND CHELATING AGENTS USEFUL IN THEIR PREPARATION | UNIVERSITY OF FLORIDA (US) | 1986-08-27 | — | — | EP | disclosed |
| WO-1986000897-A1 | NOVEL RADIOPHARMACEUTICALS AND CHELATING AGENTS USEFUL IN THEIR PREPARATION | UNIVERSITY OF FLORIDA (US) | 1986-02-13 | — | — | WO | disclosed |