Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28934054 | 0.95 | GRIK1 (0.51) | GRIK1GRIK2ALDH1A1EPHX2EPHX1 | |
| SCHEMBL692340 | 0.84 | GRIK1 (0.51) | GRIK1GRIK2EPHX2EPHX1CYP1A2 | |
| SCHEMBL322607 | 0.84 | GRIK1 (0.51) | GRIK1GRIK2EPHX2EPHX1CYP1A2 | |
| SCHEMBL2536866 | 0.83 | GRIK1 (0.50) | GRIK1GRIK2ALDH1A1SLC22A6TSHR | |
| SCHEMBL3853225 | 0.81 | GRIK1 (0.56) | GRIK1GRIK2ALDH1A1LMNA | |
| SCHEMBL2090331 | 0.80 | GRIK1 (0.54) | GRIK1GRIK2ALDH1A1EPHX2EPHX1 | |
| SCHEMBL1088357 | 0.79 | GRIK1 (0.57) | GRIK1GRIK2ALDH1A1EPHX2EPHX1 | |
| SCHEMBL165975 | 0.79 | GRIK1 (0.57) | GRIK1GRIK2ALDH1A1EPHX2EPHX1 | |
| SCHEMBL10363389 | 0.78 | GRIK1 (0.50) | GRIK1GRIK2SMN1; SMN2 | |
| SCHEMBL10363388 | 0.78 | GRIK1 (0.50) | GRIK1GRIK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977283-A | Thermosetting adhesive and method of making same | LEAR CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| WO-1998006767-A1 | THERMOSETTING ADHESIVE AND METHOD OF MAKING SAME | LEAR CORPORATION (US) | 1998-02-19 | — | — | WO | disclosed |