Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 6/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL919674 | 0.85 | APP (0.38) | PRSS1TSHR | |
| SCHEMBL919747 | 0.85 | PRSS1 (0.33) | PRSS1TSHR | |
| SCHEMBL920143 | 0.85 | APP (0.38) | PRSS1TSHR | |
| SCHEMBL919177 | 0.85 | PRSS1 (0.33) | PRSS1TSHR | |
| SCHEMBL921175 | 0.85 | APP (0.38) | PRSS1TSHR | |
| SCHEMBL920457 | 0.85 | PRSS1 (0.33) | PRSS1TSHR | |
| SCHEMBL920098 | 0.83 | TSHR (0.49) | TSHR | |
| SCHEMBL920552 | 0.83 | TSHR (0.49) | TSHR | |
| SCHEMBL9700131 | 0.83 | TSHR (0.49) | TSHR | |
| SCHEMBL920046 | 0.83 | CYP1A2 (0.42) | PRSS1NPC1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856503-A | ANTICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |