SCHEMBL920143

SCHEMBL920143

FCCCCCCCOc1cc[c]c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
APP P05067 10/20 0.38
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
PRSS1 P07477 4/20 0.33
TSHR P16473 1/20 0.33
KCNA3 P22001 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919674 1.00 APP (0.38) APPSLC6A2SLC6A4SLC6A3PRSS1
SCHEMBL921175 1.00 APP (0.38) APPSLC6A2SLC6A4SLC6A3PRSS1
SCHEMBL919682 0.98 APP (0.36) APPSLC6A2SLC6A4SLC6A3KCNA3
SCHEMBL920446 0.93 MEN1 (0.35) APPSLC6A2SLC6A4SLC6A3
SCHEMBL919994 0.87 CA12 (0.39) APPSLC6A2SLC6A4SLC6A3
SCHEMBL920457 0.86 PRSS1 (0.33) PRSS1TSHRKCNA3HDAC1HDAC2
SCHEMBL919177 0.86 PRSS1 (0.33) PRSS1TSHRKCNA3HDAC1HDAC2
SCHEMBL919747 0.86 PRSS1 (0.33) PRSS1TSHRKCNA3HDAC1HDAC2
SCHEMBL920552 0.85 TSHR (0.49) TSHR
SCHEMBL8523895 0.85 PRSS1 (0.35) PRSS1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 APP 4020/4885SLC6A2 3667/4885SLC6A4 2590/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 APP 2037/4885SLC6A2 3159/4885SLC6A4 3323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.