Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.47 |
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | CDC25C | P30307 | 3/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524322 | 0.87 | CDC25A (0.49) | CDC25ACDC25BCDC25CDUSP3TRIM24 | |
| SCHEMBL8524488 | 0.81 | CDC25A (0.45) | CDC25ACDC25BCDC25CDUSP3TRIM24 | |
| SCHEMBL8636852 | 0.81 | CDC25A (0.57) | CDC25ACDC25BCDC25CDUSP3TRIM24 | |
| SCHEMBL8524349 | 0.81 | CDC25A (0.59) | CDC25ACDC25BCDC25CDUSP3TRIM24 | |
| SCHEMBL8524438 | 0.79 | CDC25A (0.45) | CDC25ACDC25BCDC25CDUSP3TRIM24 | |
| SCHEMBL8486372 | 0.77 | CDC25A (0.72) | CDC25ACDC25BCDC25CDUSP3TRIM24 | |
| SCHEMBL8524907 | 0.76 | KDM4E (0.49) | CDC25ACDC25BCDC25CDUSP3TRIM24 | |
| SCHEMBL8484951 | 0.76 | KDM4E (0.48) | CDC25ACDC25BCDC25CDUSP3TRIM24 | |
| SCHEMBL8524191 | 0.74 | CDC25A (0.46) | CDC25ACDC25BCDC25CDUSP3TRIM24 | |
| SCHEMBL8525207 | 0.74 | KDM4E (0.42) | CDC25ACDC25BCDC25CDUSP3TRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |