Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 3/20 | 0.59 |
| ▸ | CDC25B | P30305 | 3/20 | 0.59 |
| ▸ | CDC25C | P30307 | 3/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.55 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636852 | 0.93 | CDC25A (0.57) | CDC25ACDC25BCDC25CDUSP3CYP11B1 | |
| SCHEMBL8486372 | 0.89 | CDC25A (0.72) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8524322 | 0.83 | CDC25A (0.49) | CDC25ACDC25BCDC25CDUSP3CYP11B1 | |
| SCHEMBL10658316 | 0.83 | TRIM24 (0.60) | CDC25ACDC25BCDC25CDUSP3CYP11B1 | |
| Hydrochloric Acid SCHEMBL8525221 | 0.81 | TRIM24 (0.58) | CDC25ACDC25BCDC25CDUSP3CYP11B1 | |
| SCHEMBL8483334 | 0.81 | CDC25A (0.50) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8524057 | 0.81 | CDC25A (0.47) | CDC25ACDC25BCDC25CDUSP3CYP11B1 | |
| SCHEMBL8525097 | 0.80 | CDC25A (0.46) | CDC25ACDC25BCDC25CDUSP3CYP19A1 | |
| SCHEMBL8525405 | 0.80 | CDC25A (0.51) | CDC25ACDC25BCDC25CDUSP3CYP11B1 | |
| Hydrochloric Acid SCHEMBL8524044 | 0.79 | RAB9A (0.55) | CDC25ACDC25BCDC25CDUSP3CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |