Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTR2C | P28335 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525267 | 1.00 | TAAR1 (0.52) | TAAR1TSHRHTR2CHTR2AHTR2B | |
| SCHEMBL168917 | 1.00 | TAAR1 (0.52) | TAAR1TSHRHTR2CHTR2AHTR2B | |
| SCHEMBL30036880 | 1.00 | TAAR1 (0.52) | TAAR1TSHRHTR2CHTR2AHTR2B | |
| SCHEMBL30370069 | 1.00 | TAAR1 (0.52) | TAAR1TSHRHTR2CHTR2AHTR2B | |
| SCHEMBL28338939 | 0.86 | TAAR1 (0.45) | TAAR1TSHRHTR2CHTR2AHTR2B | |
| SCHEMBL8889457 | 0.84 | TAAR1 (0.44) | TAAR1TSHRHTR2CHTR2AHTR2B | |
| SCHEMBL10779356 | 0.82 | HTR2C (0.49) | TAAR1TSHRHTR2CHTR2AHTR2B | |
| SCHEMBL37732 | 0.82 | TSHR (0.57) | TSHRHTR2ACHRM2CHRM4CHRM1 | |
| SCHEMBL27405786 | 0.77 | HTR2C (0.43) | TAAR1TSHRHTR2CHTR2AHTR2B | |
| SCHEMBL7783854 | 0.76 | HPGD (0.36) | TAAR1TSHRHTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757584-A1 | Heterocyclic substituted amides, their production and their use | Abbott GmbH & Co. KG (DE) | 2007-02-28 | — | — | EP | disclosed |
| US-5872117-A | TREATING CEREBROVASCULAR DEMENTIA, SENILE DEMENTIA, ALZHEIMER'S DEMENTIA, SEQUELAE OF ISCHEMIC ENCEPHALOPATHY AND CEREBRAL APOPLEXY | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0587194-B1 | 2-(Heterocycloalkoxy)-1-(subst.-phenyl)-ethanol derivatives as cerebral function improving agents | TOYAMA CHEMICAL CO LTD (JP) | 1997-06-04 | — | — | EP | disclosed |
| EP-0587193-B1 | 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5472984-A | 1,2-ethanediol derivative and salt thereof and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1995-12-05 | — | — | US | disclosed |
| EP-0589484-A1 | 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-03-30 | — | — | EP | disclosed |
| EP-0587194-A1 | 2-(Heterocycloalkoxy)-1-(subst.-phenyl)-ethanol derivatives as cerebral function improving agents | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-03-16 | — | — | EP | disclosed |
| EP-0587193-A1 | 1,2-Ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-5280032-A | 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-01-18 | — | — | US | disclosed |
| EP-0383281-A1 | 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1990-08-22 | — | — | EP | disclosed |