Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295289 | 0.85 | HTR2C (0.41) | HTR2CHTR2AHTR2BTRPA1ATM | |
| SCHEMBL17141386 | 0.84 | TSHR (0.40) | HTR2CHTR2AHTR2BTSHRTAAR1 | |
| SCHEMBL30370069 | 0.82 | TAAR1 (0.52) | HTR2CHTR2AHTR2BTSHRTAAR1 | |
| SCHEMBL168917 | 0.82 | TAAR1 (0.52) | HTR2CHTR2AHTR2BTSHRTAAR1 | |
| SCHEMBL30036880 | 0.82 | TAAR1 (0.52) | HTR2CHTR2AHTR2BTSHRTAAR1 | |
| SCHEMBL8525267 | 0.82 | TAAR1 (0.52) | HTR2CHTR2AHTR2BTSHRTAAR1 | |
| SCHEMBL8524358 | 0.82 | TAAR1 (0.52) | HTR2CHTR2AHTR2BTSHRTAAR1 | |
| SCHEMBL11456698 | 0.81 | HTR2C (0.36) | HTR2CHTR2AHTR2BALDH1A1CA1 | |
| SCHEMBL7055337 | 0.79 | ALDH1A1 (0.42) | HTR2CHTR2AHTR2BTSHRPBRM1 | |
| SCHEMBL7783854 | 0.76 | HPGD (0.36) | HTR2CHTR2AHTR2BTSHRTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1901971-A | Cyclopropane compounds and pharmaceutical use thereof | JAPAN TOBACCO INC (JP) | 2007-01-24 | — | — | CN | disclosed |
| US-4650908-A | Production of arylacetaldehydes | THE DOW CHEMICAL COMPANY (US) | 1987-03-17 | — | — | US | disclosed |