Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27484625 | 0.88 | NR4A1 (0.50) | NR4A1NR4A2NR4A3PRNPCDC25B | |
| SCHEMBL7916759 | 0.78 | NR4A1 (0.59) | NR4A1NR4A2NR4A3PRNPCDC25B | |
| SCHEMBL29406795 | 0.75 | NR4A1 (0.73) | NR4A1NR4A2NR4A3PRNPCDC25B | |
| SCHEMBL27985 | 0.75 | NR4A1 (0.73) | NR4A1NR4A2NR4A3PRNPCDC25B | |
| SCHEMBL28396941 | 0.73 | NR4A1 (0.70) | NR4A1NR4A2NR4A3PRNPCDC25B | |
| Bromide SCHEMBL11318433 | 0.73 | NR4A1 (0.70) | NR4A1NR4A2NR4A3PRNPCDC25B | |
| SCHEMBL28397149 | 0.73 | NR4A1 (0.70) | NR4A1NR4A2NR4A3PRNPCDC25B | |
| Hydrochloric Acid SCHEMBL2457250 | 0.73 | NR4A1 (0.70) | NR4A1NR4A2NR4A3PRNPCDC25B | |
| SCHEMBL28400347 | 0.73 | NR4A1 (0.70) | NR4A1NR4A2NR4A3PRNPCDC25B | |
| SCHEMBL28397214 | 0.73 | NR4A1 (0.70) | NR4A1NR4A2NR4A3PRNPCDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029670-A2 | AMINOCARBONYLTETRALIN AND DIHYDRONAPHTALENE DERIVATES AS THROMBIN INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-17 | — | — | WO | disclosed |