Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8523803 | 0.90 | F2 (0.38) | F2F10 | |
| SCHEMBL8515805 | 0.89 | F2 (0.40) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL8524852 | 0.81 | F2 (0.37) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8517902 | 0.77 | F2 (0.40) | F2F10 | |
| SCHEMBL8519327 | 0.74 | PIK3CA (0.39) | F2 | |
| SCHEMBL8292389 | 0.74 | F2 (0.54) | F2PRSS1 | |
| SCHEMBL8516353 | 0.69 | F2 (0.40) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL5772427 | 0.64 | F2 (0.38) | F2PRSS1PRSS2PRSS3F10 | |
| SCHEMBL8294078 | 0.61 | F2 (0.48) | F2 | |
| SCHEMBL14508582 | 0.61 | F2 (0.58) | F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1674464-A1 | Novel thrombin inhibitors | Santhera Pharmaceuticals (Schweiz) GmbH (CH) | 2006-06-28 | — | — | EP | disclosed |