Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.40 |
| ▸ | F10 | P00742 | 5/20 | 0.40 |
| ▸ | PLAT | P00750 | 4/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.40 |
| ▸ | CCR4 | P51679 | 5/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
| ▸ | PLK4 | O00444 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772427 | 0.84 | F2 (0.38) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL8523803 | 0.78 | F2 (0.38) | F2F10 | |
| SCHEMBL8292352 | 0.77 | F2 (0.43) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL8519327 | 0.73 | PIK3CA (0.39) | F2 | |
| SCHEMBL5774380 | 0.72 | ALDH1A1 (0.39) | CCNT1CDK2 | |
| SCHEMBL8262579 | 0.72 | F2 (0.40) | F2F10PLATPRSS1PRSS2 | |
| SCHEMBL8515805 | 0.71 | F2 (0.40) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8524852 | 0.69 | F2 (0.37) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8524364 | 0.69 | F2 (0.38) | F2F10PRSS1PRSS2PRSS3 | |
| SCHEMBL8292393 | 0.69 | F2 (0.40) | F2F10PLATPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1674464-A1 | Novel thrombin inhibitors | Santhera Pharmaceuticals (Schweiz) GmbH (CH) | 2006-06-28 | — | — | EP | disclosed |