Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524405 | 1.00 | CYP2C19 (0.35) | CYP2C19ALDH1A1CYP3A4RAB9AKDM4E | |
| SCHEMBL8698223 | 1.00 | CYP2C19 (0.35) | CYP2C19ALDH1A1CYP3A4RAB9AKDM4E | |
| SCHEMBL5219527 | 0.83 | PDE4B (0.36) | CYP2C19USP2L3MBTL1TDP1HTT | |
| SCHEMBL6000705 | 0.83 | PDE4B (0.36) | CYP2C19USP2L3MBTL1TDP1HTT | |
| SCHEMBL2062037 | 0.80 | MAPT (0.45) | CYP2C19ALDH1A1CYP3A4RAB9AKDM4E | |
| SCHEMBL2062036 | 0.80 | MAPT (0.45) | CYP2C19ALDH1A1CYP3A4RAB9AKDM4E | |
| SCHEMBL1119857 | 0.78 | HPGD (0.44) | CYP2C19ALDH1A1SMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL8525588 | 0.78 | HPGD (0.44) | CYP2C19ALDH1A1SMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL4970172 | 0.78 | HPGD (0.44) | CYP2C19ALDH1A1SMN1; SMN2USP2L3MBTL1 | |
| SCHEMBL2063614 | 0.78 | MAPT (0.43) | ALDH1A1CYP3A4KDM4ETSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |