Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970172 | 1.00 | HPGD (0.44) | HPGDL3MBTL1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL1119857 | 1.00 | HPGD (0.44) | HPGDL3MBTL1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL193814 | 0.81 | RAD52 (0.41) | HPGDL3MBTL1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL30303023 | 0.81 | RAD52 (0.41) | HPGDL3MBTL1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL193813 | 0.81 | RAD52 (0.41) | HPGDL3MBTL1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL26477325 | 0.81 | RARB (0.35) | RARBRARGRXRANOTUMTYMS | |
| SCHEMBL24803361 | 0.79 | KDM4E (0.33) | RARBRARGRXRATYMS | |
| SCHEMBL30336848 | 0.79 | KDM4E (0.33) | RARBRARGRXRATYMS | |
| SCHEMBL8524402 | 0.78 | CYP2C19 (0.35) | HPGDL3MBTL1NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8698223 | 0.78 | CYP2C19 (0.35) | HPGDL3MBTL1NPSR1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |