Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CDC25A | P30304 | 3/20 | 0.40 |
| ▸ | CDC25B | P30305 | 3/20 | 0.40 |
| ▸ | CDC25C | P30307 | 3/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525207 | 0.82 | KDM4E (0.42) | KDM4ESMN1; SMN2RAB9ANPC1CYP19A1 | |
| SCHEMBL8524649 | 0.82 | RARA (0.44) | KDM4ESMN1; SMN2RAB9ANPC1CYP19A1 | |
| SCHEMBL8524488 | 0.82 | CDC25A (0.45) | KDM4ESMN1; SMN2RAB9ANPC1CYP19A1 | |
| SCHEMBL8524438 | 0.82 | CDC25A (0.45) | KDM4ESMN1; SMN2RAB9ANPC1CYP19A1 | |
| SCHEMBL8524583 | 0.79 | CDC25A (0.44) | KDM4ESMN1; SMN2RAB9ANPC1CYP19A1 | |
| SCHEMBL8483824 | 0.78 | CDC25A (0.56) | KDM4ESMN1; SMN2RAB9ANPC1CYP19A1 | |
| SCHEMBL8525097 | 0.76 | CDC25A (0.46) | KDM4ESMN1; SMN2RAB9ANPC1CYP19A1 | |
| Hydrochloric Acid SCHEMBL8525666 | 0.74 | KDM4E (0.44) | KDM4ESMN1; SMN2RAB9ANPC1CYP19A1 | |
| SCHEMBL8524907 | 0.74 | KDM4E (0.49) | KDM4ESMN1; SMN2RAB9ANPC1CYP19A1 | |
| SCHEMBL8525211 | 0.73 | CDC25A (0.43) | KDM4ESMN1; SMN2RAB9ANPC1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |