Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | F9 | P00740 | 3/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491301 | 0.85 | F9 (0.42) | PDE2AF9SYKMEN1KMT2A | |
| SCHEMBL8524146 | 0.83 | DHODH (0.38) | PDE2AF9SYKEPHX2SMYD3 | |
| SCHEMBL8492423 | 0.82 | PDE2A (0.38) | PDE2AF9SYKEPHX2MEN1 | |
| SCHEMBL8524536 | 0.82 | PDE2A (0.38) | PDE2AF9SYKMEN1KMT2A | |
| SCHEMBL9114961 | 0.78 | DHODH (0.37) | PDE2AEPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7627829 | 0.78 | DHODH (0.34) | PDE2AEPHX2SMN1; SMN2ALDH1A1NAMPT | |
| SCHEMBL9115225 | 0.78 | DHODH (0.34) | PDE2AEPHX2NAMPT | |
| SCHEMBL8493685 | 0.77 | DHODH (0.36) | PDE2AEPHX2SMN1; SMN2NAMPT | |
| SCHEMBL8491851 | 0.77 | DHODH (0.47) | PDE2AEPHX2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1822437 | 0.76 | PDE2A (0.43) | PDE2ASYKEPHX2SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |