Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | F9 | P00740 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491301 | 0.85 | F9 (0.42) | PDE2ACRACR2AF9GPR119SYK | |
| SCHEMBL8524449 | 0.83 | PDE2A (0.39) | PDE2AEPHX2F9GPR119SYK | |
| SCHEMBL8492423 | 0.83 | PDE2A (0.38) | PDE2AEPHX2F9GPR119SYK | |
| SCHEMBL8524536 | 0.82 | PDE2A (0.38) | PDE2ACTSSHSD11B1F9GPR119 | |
| SCHEMBL8525576 | 0.82 | DHODH (0.44) | DHODHPDE2AEPHX2KDM4EALDH1A1 | |
| SCHEMBL8166576 | 0.81 | NR1H4 (0.39) | MAPK10CTSSLRRK2HSD11B1NR1H4 | |
| SCHEMBL1822485 | 0.81 | PDE2A (0.38) | DHODHPDE2AEPHX2CRACR2ASYK | |
| SCHEMBL8525429 | 0.78 | NR1H4 (0.40) | MAPK10NR1H4F9GPR119SMN1; SMN2 | |
| SCHEMBL8494851 | 0.78 | DHODH (0.53) | DHODHEPHX2CRACR2AKDM4EALDH1A1 | |
| SCHEMBL9116214 | 0.78 | DHODH (0.44) | DHODHEPHX2CRACR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |