Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.61 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.61 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HINT1 | P49773 | 4/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | PNP | P00491 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | GSK3A | P49840 | 2/20 | 0.55 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanosine SCHEMBL5027190 | 1.00 | HPGD (0.63) | HPGDP2RY2P2RY4P2RY6POLB | |
| Guanosine SCHEMBL4874332 | 0.93 | DNMT1 (0.63) | HPGDP2RY2P2RY4P2RY6SMN1; SMN2 | |
| Guanosine SCHEMBL27992737 | 0.93 | DNMT1 (0.63) | HPGDP2RY2P2RY4P2RY6SMN1; SMN2 | |
| Deoxyguanosine SCHEMBL27992930 | 0.93 | DNMT1 (0.63) | HPGDP2RY2P2RY4P2RY6SMN1; SMN2 | |
| Deoxyguanosine SCHEMBL22992402 | 0.92 | POLB (0.67) | P2RY2P2RY4P2RY6POLBPNP | |
| Deoxyguanosine SCHEMBL9396414 | 0.92 | POLB (0.67) | P2RY2P2RY4P2RY6POLBPNP | |
| Deoxyguanosine SCHEMBL20615 | 0.92 | POLB (0.67) | P2RY2P2RY4P2RY6POLBPNP | |
| Deoxyguanosine SCHEMBL23225364 | 0.92 | POLB (0.67) | P2RY2P2RY4P2RY6POLBPNP | |
| Deoxyguanosine SCHEMBL10068103 | 0.92 | POLB (0.67) | P2RY2P2RY4P2RY6POLBPNP | |
| Deoxyguanosine SCHEMBL23892102 | 0.92 | POLB (0.67) | P2RY2P2RY4P2RY6POLBPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001817-A | Pharmaceutical composition comprised of cisplatin, and processes for making and using same | UNITECH PHARMACEUTICALS, INC. (US) | 1999-12-14 | — | — | US | disclosed |