Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 5/20 | 0.63 |
| ▸ | DNMT3B | Q9UBC3 | 3/20 | 0.63 |
| ▸ | FPR2 | P25090 | 2/20 | 0.63 |
| ▸ | DPP4 | P27487 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.63 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.63 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.63 |
| ▸ | GAPDH | P04406 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.63 |
| ▸ | STAT6 | P42226 | 1/20 | 0.63 |
| ▸ | PI4KA | P42356 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.63 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deoxyguanosine SCHEMBL27992930 | 1.00 | DNMT1 (0.63) | DNMT1DNMT3BFPR2DPP4MEN1 | |
| Guanosine SCHEMBL27992737 | 1.00 | DNMT1 (0.63) | DNMT1DNMT3BFPR2DPP4MEN1 | |
| Guanosine SCHEMBL5027190 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDP2RY2P2RY4P2RY6 | |
| Guanosine SCHEMBL8524537 | 0.93 | HPGD (0.63) | SMN1; SMN2HPGDP2RY2P2RY4P2RY6 | |
| Deoxyguanosine SCHEMBL6372750 | 0.93 | PNP (0.61) | DNMT1DNMT3BFPR2SMN1; SMN2STING1 | |
| Guanosine SCHEMBL6856847 | 0.92 | ADORA3 (0.75) | DPP4MEN1SLC28A1MAP3K7SLC28A2 | |
| Guanosine SCHEMBL7722707 | 0.92 | ADORA3 (0.75) | DPP4MEN1SLC28A1MAP3K7SLC28A2 | |
| Guanosine SCHEMBL531212 | 0.92 | ADORA3 (0.75) | DPP4MEN1SLC28A1MAP3K7SLC28A2 | |
| Adenosine SCHEMBL5150670 | 0.89 | ADORA3 (0.80) | DNMT1DNMT3BFPR2DPP4MEN1 | |
| Adenosine SCHEMBL3207685 | 0.89 | P2RY2 (0.70) | SMN1; SMN2P2RY2P2RY4P2RY6DTYMK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080145372-A1 | Bioreductively-Activated Prodrugs | ANGIOGENE, PHARMACEUTICALS LIMITED (GB) | 2008-06-19 | — | — | US | claimed |
| EP-1799698-A1 | BIOREDUCTIVELY-ACTIVATED PRODRUGS | Angiogene Pharmaceuticals Limited (GB) | 2007-06-27 | — | — | EP | claimed |
| WO-2006032921-A1 | BIOREDUCTIVELY-ACTIVATED PRODRUGS | ANGIOGENE PHARMACEUTICALS LIMITED (GB) | 2006-03-30 | — | — | WO | claimed |
| US-20080145372-A1 | Bioreductively-Activated Prodrugs | ANGIOGENE, PHARMACEUTICALS LIMITED (GB) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080145372-A1 | Bioreductively-Activated Prodrugs | NME2, PNP, NUDT1 | DNMT1 3747/4885DNMT3B 3356/4885FPR2 2525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.