SCHEMBL8524658

SCHEMBL8524658

c1ccc([Al](c2ccccc2)[Al](c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
TSHR P16473 5/20 0.35
TDP1 Q9NUW8 4/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
ALOX12 P18054 2/20 0.35
CA12 O43570 1/20 0.35
GLA P06280 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA14 Q9ULX7 1/20 0.35
LMNA P02545 1/20 0.35
ACHE P22303 1/20 0.35
CA7 P43166 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
HSD17B10 Q99714 2/20 0.33
CYP2A6 P11509 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49939 0.75 ALDH1A1 (0.40) ALDH1A1TSHRTDP1CA1CA2
Ammonia Solution, Strong SCHEMBL6301069 0.72 ALDH1A1 (0.38) ALDH1A1TSHRTDP1CA1CA2
Hydrochloric Acid SCHEMBL27449759 0.72 ALDH1A1 (0.38) ALDH1A1TSHRTDP1CA1CA2
SCHEMBL31585928 0.72 ALDH1A1 (0.38) ALDH1A1TSHRTDP1CA1CA2
SCHEMBL28105654 0.72 ALDH1A1 (0.38) ALDH1A1TSHRTDP1CA1CA2
SCHEMBL2166400 0.69 ALDH1A1 (0.35) ALDH1A1TSHRTDP1CA1CA2
SCHEMBL1538843 0.69 ALDH1A1 (0.39) ALDH1A1TSHRTDP1CA1CA2
SCHEMBL1624424 0.69
SCHEMBL150127 0.69 TSHR (0.39) ALDH1A1TSHRTDP1CA1CA2
SCHEMBL1539021 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999030821-A1 CATALYST COMPOSITIONS FOR OLEFIN POLYMERIZATION BASED ON METALLOCENE COMPLEXES AND NOVEL COCATALYSTS PRODUCED FROM TRIALKYLALUMINUM COMPOUNDS, STERICALLY HINDERED PHENOLS, AND WATER MOBIL OIL CORPORATION (US) 1999-06-24 WO disclosed