Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524417 | 1.00 | SLC15A1 (0.39) | SLC15A1CCNT1CDK9ADORA2BATM | |
| SCHEMBL8524692 | 1.00 | SLC15A1 (0.39) | SLC15A1CCNT1CDK9ADORA2BATM | |
| SCHEMBL8524414 | 1.00 | SLC15A1 (0.39) | SLC15A1CCNT1CDK9ADORA2BATM | |
| SCHEMBL7608537 | 0.81 | CCNT1 (0.45) | SLC15A1CCNT1CDK9ADORA2BCHRM2 | |
| SCHEMBL7608539 | 0.81 | CCNT1 (0.45) | SLC15A1CCNT1CDK9ADORA2BCHRM2 | |
| SCHEMBL7608534 | 0.81 | CCNT1 (0.45) | SLC15A1CCNT1CDK9ADORA2BCHRM2 | |
| SCHEMBL8580239 | 0.80 | IDO1 (0.38) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8580236 | 0.80 | IDO1 (0.38) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8662326 | 0.80 | IDO1 (0.38) | ALDH1A1CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6950900 | 0.79 | SLC15A1 (0.42) | SLC15A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912356-A | HERPES VIRUS | GLAXO WELLCOME INC. (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0630368-B1 | ANTIVIRAL NUCLEOSIDE ANALOGUES | WELLCOME FOUND (GB) | 1998-09-09 | — | — | EP | disclosed |
| US-5534535-A | ANTIVIRAL ANALOGS WITH SUBSTITUTED BENZIMIDAZOLE BASE | BURROUGHS WELLCOME CO. (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0630368-A1 | ANTIVIRAL NUCLEOSIDE ANALOGUES | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-12-28 | — | — | EP | disclosed |
| WO-1993018009-A1 | ANTIVIRAL NUCLEOSIDE ANALOGUES | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-09-16 | — | — | WO | disclosed |