Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411151 | 0.83 | TAAR1 (0.58) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL3243396 | 0.81 | NUDT1 (0.58) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL29609269 | 0.81 | NUDT1 (0.58) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL2412835 | 0.77 | MAPT (0.47) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL3241384 | 0.77 | MAPT (0.40) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL3247948 | 0.75 | TAAR1 (0.56) | MAPTLMNATP53POLBNPC1 | |
| SCHEMBL2409626 | 0.74 | SLC2A1 (0.56) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL4415371 | 0.74 | APP (0.50) | MAPTLMNANPC1RAB9AKDM4E | |
| SCHEMBL8253278 | 0.73 | MAPT (0.74) | MEN1KMT2AMAPTLMNATP53 | |
| SCHEMBL3246140 | 0.72 | MAPT (0.58) | MEN1KMT2AMAPTLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0945443-A1 | HIV inhibiting pyrimidine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-09-29 | — | — | EP | disclosed |