Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 8/20 | 0.72 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | STS | P08842 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14716821 | 0.98 | HSD17B3 (0.73) | HSD17B3HTR7KMT2ASTSL3MBTL1 | |
| SCHEMBL19047793 | 0.98 | HSD17B3 (0.73) | HSD17B3HTR7KMT2ASTSL3MBTL1 | |
| SCHEMBL2082766 | 0.98 | HSD17B3 (0.73) | HSD17B3HTR7KMT2ASTSL3MBTL1 | |
| SCHEMBL7761755 | 0.98 | HSD17B3 (0.73) | HSD17B3HTR7KMT2ASTSL3MBTL1 | |
| SCHEMBL8510520 | 0.98 | HSD17B3 (0.73) | HSD17B3HTR7KMT2ASTSL3MBTL1 | |
| SCHEMBL4839086 | 0.94 | HSD17B3 (0.71) | HSD17B3HTR7KMT2ASTSL3MBTL1 | |
| SCHEMBL19757422 | 0.93 | HSD17B3 (0.67) | HSD17B3HTR7KMT2ASTSL3MBTL1 | |
| SCHEMBL19757419 | 0.93 | HSD17B3 (0.67) | HSD17B3HTR7KMT2ASTSL3MBTL1 | |
| SCHEMBL15657847 | 0.93 | HSD17B3 (0.67) | HSD17B3HTR7KMT2ASTSL3MBTL1 | |
| SCHEMBL19757459 | 0.93 | HSD17B3 (0.67) | HSD17B3HTR7KMT2ASTSL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444458-A | Method for realizing migration of remote aromatic heterocycle and direct alkyl heteroaryl of terminal olefin | 南京工业大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-103613487-B | Method for preparing alpha-alkylated ketone by coupling alcohol with alpha-methyl/methylene ketone | UNIV NORTHWEST NORMAL | 2015-06-17 | — | — | CN | disclosed |
| CN-103613487-A | Method for preparing alpha-alkylated ketone by coupling alcohol with alpha-methyl/methylene ketone | UNIV NORTHWEST NORMAL | 2014-03-05 | — | — | CN | disclosed |
| US-7964599-B2 | Therapeutic compounds | ALLERGAN, INC. (US) | 2011-06-21 | — | — | US | disclosed |
| US-20090281104-A1 | Therapeutic Compounds | ALLERGAN, INC. (US) | 2009-11-12 | — | — | US | disclosed |
| US-7476755-B2 | Therapeutic compounds | ALLERGAN, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20070259929-A1 | Therapeutic Compounds | ALLERGAN, INC. | 2007-11-08 | — | — | US | disclosed |
| EP-0766666-B1 | BENZYLSULFIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-03-17 | — | — | EP | disclosed |
| US-5728699-A | Benzylsulfide derivative, process for its production and pesticide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-03-17 | — | — | US | disclosed |
| EP-0766666-A1 | BENZYLSULFIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-04-09 | — | — | EP | disclosed |
| WO-1996033168-A1 | BENZYLSULFIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-10-24 | — | — | WO | disclosed |
| US-5008452-A | Antidepressants, sedatives and anticonvulsants | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1991-04-16 | — | — | US | disclosed |
| US-4235931-A | ANTIDEPRESSANTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1980-11-25 | — | — | US | disclosed |
| US-4192818-A | ANTIDEPRESSANTS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1980-03-11 | — | — | US | disclosed |
| US-3937841-A | AMINO-OXIME COMPOUNDS | U.S. PHILIPS CORPORATION (US) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259929-A1 | Therapeutic Compounds | PIGO, CYC1, COXFA4L2 | HSD17B3 2090/4885HTR7 1017/4885KMT2A 4709/4885 |
| US-20090281104-A1 | Therapeutic Compounds | SLC10A1, ABCB11, GUSB | HSD17B3 1285/4885HTR7 1718/4885KMT2A 2896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.