Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | CHAT | P28329 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288182 | 0.78 | NFE2L2 (0.48) | TRPA1NFE2L2CHATMAOB | |
| SCHEMBL288181 | 0.78 | NFE2L2 (0.48) | TRPA1NFE2L2CHATMAOB | |
| SCHEMBL919379 | 0.77 | NFE2L2 (0.57) | TRPA1NFE2L2CHATMAOB | |
| SCHEMBL4247302 | 0.76 | CNR2 (0.31) | — | |
| SCHEMBL28620792 | 0.76 | CNR2 (0.31) | — | |
| SCHEMBL44503 | 0.73 | NFE2L2 (0.68) | TRPA1NFE2L2CHATMAOB | |
| (Z)-1,2-Diphenylethene SCHEMBL7653143 | 0.73 | NFE2L2 (0.68) | TRPA1NFE2L2CHATMAOB | |
| SCHEMBL44502 | 0.73 | NFE2L2 (0.68) | TRPA1NFE2L2CHATMAOB | |
| (Z)-1,2-Diphenylethene SCHEMBL7653150 | 0.73 | NFE2L2 (0.68) | TRPA1NFE2L2CHATMAOB | |
| SCHEMBL9540538 | 0.73 | NFE2L2 (0.68) | TRPA1NFE2L2CHATMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886044-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1999-03-23 | — | — | US | disclosed |
| US-5780483-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-14 | — | — | US | disclosed |