Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8525302 | 0.84 | F2 (0.56) | ALDH1A1HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL8492087 | 0.81 | F2 (0.43) | ALDH1A1HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL8491517 | 0.81 | F2 (0.60) | ALDH1A1HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL8525762 | 0.81 | F2 (0.51) | ALDH1A1HDAC2HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL8524038 | 0.79 | F2 (0.56) | ALDH1A1F2ST14MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8525281 | 0.79 | F2 (0.46) | ALDH1A1HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL8489800 | 0.78 | F2 (0.53) | ALDH1A1HDAC2HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL8525508 | 0.76 | ALDH1A1 (0.39) | ALDH1A1HDAC2HDAC3HDAC4HDAC1 | |
| SCHEMBL8524542 | 0.76 | F2 (0.49) | ALDH1A1HDAC2HDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL8525669 | 0.76 | F2 (0.51) | ALDH1A1HDAC2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029670-A2 | AMINOCARBONYLTETRALIN AND DIHYDRONAPHTALENE DERIVATES AS THROMBIN INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-17 | — | — | WO | disclosed |