Phenol

Phenol

SCHEMBL8525396

CC(=O)Cc1ccccc1O.Oc1ccccc1.Oc1ccccc1.Oc1ccccc1.Oc1ccccc1.Oc1ccccc1.Oc1ccccc1.Oc1ccccc1.Oc1ccccc1.Oc1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.53
IDO1 P14902 2/20 0.47
KEAP1 Q14145 1/20 0.46
HSPA5 P11021 1/20 0.45
IAPP P10997 1/20 0.44
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
CA2 P00918 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
GLA P06280 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA9 Q16790 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CA14 Q9ULX7 1/20 0.42
FNTA P49354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL5397005 1.00 AKR1B1 (0.64) AKR1B1L3MBTL1IDO1KEAP1HSPA5
Phenol SCHEMBL6531501 1.00 AKR1B1 (0.64) AKR1B1L3MBTL1IDO1KEAP1HSPA5
SCHEMBL266802 0.92 AKR1B1 (0.68) AKR1B1L3MBTL1IDO1HSPA5IAPP
SCHEMBL30176200 0.92 AKR1B1 (0.68) AKR1B1L3MBTL1IDO1HSPA5IAPP
Ethylbenzene SCHEMBL28226401 0.84 AKR1B1 (0.58) AKR1B1L3MBTL1HSPA5IAPPLMNA
Benzene SCHEMBL10992898 0.81 L3MBTL1 (0.60) AKR1B1L3MBTL1IAPPLMNAPOLB
Phenol SCHEMBL2808100 0.80 AKR1B1 (0.58) AKR1B1IDO1KEAP1LMNAGAA
Phenol SCHEMBL7950353 0.79 AKR1B1 (0.56) AKR1B1IDO1KEAP1HSPA5CA2
SCHEMBL29676820 0.79 AKR1B1 (0.61) AKR1B1L3MBTL1LMNAGAAMAPT
Phenol SCHEMBL1276616 0.79 AKR1B1 (0.56) AKR1B1IDO1KEAP1HSPA5CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0676237-B1 Modified ion exchange resins and use thereof MITSUBISHI CHEM CORP (JP) 1999-03-17 EP disclosed
US-5589517-A N,N-DI-SUBSTITITUTED MERCAPTOALKYLAMINE SULFONIC ACID ION EXCHANGE RESIN AS CATALYST FOR CONDENSATION REACTION OF A PHENOL AND A KETONE TO PRODUCE A BISPHENOL MITSUBISHI CHEMICAL CORPORATION (JP) 1996-12-31 US disclosed
EP-0676237-A1 Modified ion exchange resins and use thereof MITSUBISHI CHEMICAL CORPORATION (JP) 1995-10-11 EP disclosed