Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 12/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101003 | 0.91 | TUBB4A (0.47) | PTAFRKMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL8108757 | 0.91 | TUBB4A (0.47) | PTAFRKMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL8108754 | 0.91 | TUBB4A (0.47) | PTAFRKMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL8115979 | 0.81 | TUBB4A (0.56) | PTAFRKMT2AMEN1TUBB4ATUBB | |
| SCHEMBL8109862 | 0.81 | TUBB4A (0.56) | PTAFRKMT2AMEN1TUBB4ATUBB | |
| SCHEMBL8115981 | 0.81 | TUBB4A (0.56) | PTAFRKMT2AMEN1TUBB4ATUBB | |
| SCHEMBL9373213 | 0.78 | TUBB4A (0.43) | PTAFRKMT2ATUBB4ATUBBTUBA3C | |
| SCHEMBL8108936 | 0.78 | PTAFR (0.64) | PTAFR | |
| SCHEMBL8110382 | 0.78 | PTAFR (0.64) | PTAFR | |
| SCHEMBL8110390 | 0.78 | PTAFR (0.64) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856323-A | PAF RECEPTOR ANTAGONISTS, INHIBITING THE ENZYME 5-LIPOXYGENASE | CYTOMED, INC. (US) | 1999-01-05 | — | — | US | disclosed |