Ethylbenzene

Ethylbenzene

SCHEMBL8525583

CCc1ccccc1.O=C(O)C(F)(F)F

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.61
CES1 P23141 6/20 0.55
FAAH O00519 3/20 0.50
PPARG P37231 1/20 0.49
PPARA Q07869 1/20 0.49
CPA1 P15085 1/20 0.49
ALDH1A1 P00352 2/20 0.48
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
NCOR2 Q9Y618 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.45
HIF1A Q16665 1/20 0.45
KEAP1 Q14145 1/20 0.45
CYP2C19 P33261 2/20 0.45
CYP1A2 P05177 2/20 0.44
MAPT P10636 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylbenzene SCHEMBL11663922 0.88 TP53 (0.56) TP53CES1FAAHPPARGPPARA
Ethylbenzene SCHEMBL27323077 0.84 TP53 (0.78) TP53CES1PPARGPPARAALDH1A1
Trifluoroacetic Acid SCHEMBL7850280 0.82 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2CYP2C19CYP1A2NPC1
Ethylbenzene SCHEMBL28436435 0.81 TP53 (0.74) TP53CES1PPARGPPARAALDH1A1
Ethylbenzene SCHEMBL27596106 0.81 TP53 (0.74) TP53CES1PPARGPPARAALDH1A1
Ethylbenzene SCHEMBL10979046 0.81 TP53 (0.74) TP53CES1PPARGPPARAALDH1A1
Ethylbenzene SCHEMBL216251 0.81 TP53 (0.93) TP53CES1PPARGPPARAALDH1A1
Ethylbenzene SCHEMBL28056495 0.81 TP53 (0.93) TP53CES1PPARGPPARAALDH1A1
Ethylbenzene SCHEMBL9474534 0.81 TP53 (0.93) TP53CES1PPARGPPARAALDH1A1
Ethylbenzene SCHEMBL28009971 0.81 TP53 (0.93) TP53CES1PPARGPPARAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113620934-B Alkylation method of nitrogen-containing heterocyclic compound in visible light-mediated micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2023-07-07 CN claimed
CN-113620934-B Alkylation method of nitrogen-containing heterocyclic compound in visible light-mediated micro-reaction device 南京先进生物材料与过程装备研究院有限公司 2023-07-07 CN disclosed
US-5919756-A CHLORORIENTICIN A ANTIBIOTIC ELI LILLY AND COMPANY (US) 1999-07-06 US disclosed