Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525600 | 1.00 | TAAR1 (0.42) | TAAR1AOC3SIGMAR1MEN1KMT2A | |
| SCHEMBL8494568 | 0.81 | USP2 (0.40) | TAAR1AOC3MAPTGAASMN1; SMN2 | |
| SCHEMBL28045393 | 0.81 | MEN1 (0.41) | MEN1KMT2AMAPTTDP1GAA | |
| SCHEMBL8494566 | 0.81 | USP2 (0.40) | TAAR1AOC3MAPTGAASMN1; SMN2 | |
| SCHEMBL8497030 | 0.81 | GAA (0.47) | MEN1KMT2AMAPTTDP1GAA | |
| SCHEMBL8495505 | 0.77 | MAPT (0.53) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL28045549 | 0.77 | GAA (0.41) | MEN1KMT2AMAPTTDP1GAA | |
| SCHEMBL8495502 | 0.77 | MAPT (0.53) | MEN1KMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL22473611 | 0.77 | MEN1 (0.44) | MEN1KMT2AMAPTTDP1GAA | |
| SCHEMBL28045397 | 0.76 | GAA (0.40) | MEN1KMT2AMAPTTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999040062-A1 | HYDRAZONE DERIVATIVES | NOVO NORDISK A/S (DK) | 1999-08-12 | — | — | WO | disclosed |