Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045549 | 0.98 | GAA (0.41) | GAAMEN1KMT2AMAPTNPC1 | |
| SCHEMBL28045393 | 0.86 | MEN1 (0.41) | GAAMEN1KMT2AMAPTNPC1 | |
| SCHEMBL22473611 | 0.78 | MEN1 (0.44) | GAAMEN1KMT2AMAPTNPC1 | |
| SCHEMBL8525600 | 0.76 | TAAR1 (0.42) | GAAMEN1KMT2AMAPTNPC1 | |
| SCHEMBL8525598 | 0.76 | TAAR1 (0.42) | GAAMEN1KMT2AMAPTNPC1 | |
| Methanesulfonamide SCHEMBL4347821 | 0.75 | MAPT (0.36) | GAAMEN1KMT2AMAPTNPC1 | |
| Heptane SCHEMBL11601626 | 0.72 | KDM4A (0.47) | GAAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5071847 | 0.72 | SOAT2 (0.43) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11761790 | 0.72 | SOAT2 (0.40) | MEN1KMT2ASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL8497030 | 0.72 | GAA (0.47) | GAAMEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272793-B | Method for synthesizing aryl hydrazone | 南京理工大学 | 2017-02-15 | — | — | CN | disclosed |
| CN-105272793-A | Method for synthesizing aryl hydrazone | UNIV NANJING SCIENCE & TECH | 2016-01-27 | — | — | CN | disclosed |