Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215484 | 0.80 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8525764 | 0.80 | PTGS2 (0.84) | PTGS2PTGS1 | |
| SCHEMBL5311830 | 0.78 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL4097790 | 0.76 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL7212040 | 0.75 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL462723 | 0.74 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL15052403 | 0.74 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL15051904 | 0.74 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL4088205 | 0.73 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL7215275 | 0.73 | PTGS2 (1.00) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946507-A1 | SUBSTITUTED PYRROLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998025896-A1 | SUBSTITUTED PYRROLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-06-18 | — | — | WO | disclosed |