Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525055 | 0.89 | MAPK10 (0.35) | MAPK10ABCB1GPBAR1MAPTSMN1; SMN2 | |
| SCHEMBL8524143 | 0.87 | LRRK2 (0.38) | MAPK10MAPTALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8525843 | 0.86 | PTGER1 (0.39) | MAPK10ABCB1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8525951 | 0.86 | MAPT (0.41) | MAPK10ABCB1MAPTALDH1A1HPGD | |
| SCHEMBL8524806 | 0.85 | MAPK10 (0.39) | MAPK10LMNAMAPTALDH1A1HPGD | |
| SCHEMBL8524723 | 0.85 | MAPK10 (0.35) | MAPK10ABCB1PTGER4GPBAR1LMNA | |
| SCHEMBL8652662 | 0.82 | MAPT (0.36) | MAPK10ABCB1GPBAR1MAPTSMN1; SMN2 | |
| SCHEMBL8524608 | 0.82 | MAPT (0.35) | MAPK10GPBAR1LMNAMAPTALDH1A1 | |
| SCHEMBL8524684 | 0.81 | MAPT (0.33) | MAPK10ABCB1PTGER4LMNAMAPT | |
| SCHEMBL8524279 | 0.81 | LRRK2 (0.35) | MAPK10PTGER4LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |