Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525951 | 0.89 | MAPT (0.41) | MAPK10ABCB1SMN1; SMN2HSP90AA1MAPT | |
| SCHEMBL8652662 | 0.87 | MAPT (0.36) | MAPK10ABCB1SMN1; SMN2HSP90AA1MAPT | |
| SCHEMBL8524369 | 0.87 | PTGER1 (0.44) | PTGER1ABCB1LMNASMN1; SMN2HSP90AA1 | |
| SCHEMBL8524143 | 0.87 | LRRK2 (0.38) | MAPK10SMN1; SMN2HSP90AA1MAPTHTT | |
| SCHEMBL8525817 | 0.86 | MAPK10 (0.36) | MAPK10ABCB1LMNASMN1; SMN2HSP90AA1 | |
| SCHEMBL8525613 | 0.86 | MAPK10 (0.40) | PTGER1MAPK10LMNASMN1; SMN2HSP90AA1 | |
| SCHEMBL8525055 | 0.85 | MAPK10 (0.35) | MAPK10ABCB1SMN1; SMN2HSP90AA1MAPT | |
| SCHEMBL8524723 | 0.85 | MAPK10 (0.35) | MAPK10ABCB1LMNASMN1; SMN2HSP90AA1 | |
| SCHEMBL8524608 | 0.82 | MAPT (0.35) | MAPK10LMNASMN1; SMN2HSP90AA1MAPT | |
| SCHEMBL8524684 | 0.81 | MAPT (0.33) | MAPK10ABCB1LMNASMN1; SMN2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |