Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 8/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8524680 | 0.74 | AHR (0.57) | AHRPDK2NPC1MAPK13MAPK12 | |
| SCHEMBL18826462 | 0.70 | KDM4E (0.43) | CYP19A1NPSR1 | |
| SCHEMBL3646873 | 0.69 | NPSR1 (0.44) | AHRPDK2NPC1BRD4CREBBP | |
| Oxindole SCHEMBL11087237 | 0.69 | AHR (0.78) | AHRPDK2NPC1MAPK13MAPK12 | |
| Alcohol SCHEMBL10571326 | 0.68 | NPC1 (0.79) | AHRPDK2NPC1MAPK13MAPK12 | |
| SCHEMBL19289267 | 0.67 | ADRA2A (0.41) | ADRA2AHTR1A | |
| SCHEMBL23674847 | 0.67 | NPSR1 (0.52) | AHRPDK2NPC1MAPK13MAPK12 | |
| SCHEMBL21061671 | 0.67 | AHR (0.52) | AHRPDK2NPC1MAPK13MAPK12 | |
| Oxindole SCHEMBL8866522 | 0.67 | AHR (0.72) | AHRPDK2NPC1MAPK13MAPK12 | |
| SCHEMBL30100714 | 0.67 | NPSR1 (0.52) | AHRPDK2NPC1MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |