Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.37 |
| ▸ | EPOR | P19235 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 2/20 | 0.34 |
| ▸ | MC5R | P33032 | 2/20 | 0.34 |
| ▸ | MC3R | P41968 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650060 | 0.92 | TDP1 (0.41) | TDP1MEN1KMT2AEPORHTR2A | |
| SCHEMBL8650581 | 0.91 | TDP1 (0.43) | TDP1MEN1KMT2AEPORHTR2A | |
| SCHEMBL8126608 | 0.90 | TDP1 (0.41) | TDP1MEN1KMT2AEPORHTR2A | |
| SCHEMBL8119409 | 0.86 | EPOR (0.43) | TDP1MEN1KMT2AEPORMC4R | |
| SCHEMBL8528953 | 0.86 | TDP1 (0.41) | TDP1MEN1KMT2ANR1H3RORC | |
| SCHEMBL8127789 | 0.86 | TDP1 (0.46) | TDP1MEN1KMT2ANR1H3EPOR | |
| SCHEMBL7039838 | 0.85 | TDP1 (0.36) | TDP1MEN1KMT2ANR1H3RORC | |
| Hydrochloric Acid SCHEMBL8120628 | 0.84 | EPOR (0.41) | TDP1MEN1KMT2AEPORMC4R | |
| SCHEMBL8651940 | 0.84 | EPOR (0.56) | EPOR | |
| SCHEMBL9196210 | 0.82 | TACR1 (0.36) | TDP1MEN1KMT2AEPORHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | disclosed |